Principal Statistical Programmer
Job description
Job Title: Principal Statistical Programmer
Job Title:Job Location: Durham, North Carolina, United States of America
Job Location:Job Location Type: Remote
Job Location Type:Job Contract Type: Full-time
Job Contract Type:Job Seniority Level:
Job Seniority Level:Position Summary
Position SummaryWe are seeking a Principal Statistical Programmer to provide full end‑to‑end statistical programming support across clinical development programs. This role requires deep technical expertise, leadership, and hands‑on delivery, covering SDTM, ADaM, TLF development, and regulatory submission support. The Principal Statistical Programmer will serve as a subject matter expert, ensure high‑quality deliverables, and contribute to programming standards and best practices.
Principal Statistical Programmerfull end‑to‑end statistical programming supportSDTM, ADaM, TLF development, and regulatory submission supportKey Responsibilities
Key Responsibilities- Provide end‑to‑end statistical programming support for clinical studies from study setup through submission
Provide end‑to‑end statistical programming support for clinical studies from study setup through submission
end‑to‑end statistical programming support- Lead and perform development and validation of:SDTM datasetsADaM datasetsTables, Listings, and Figures (TLFs)
Lead and perform development and validation of:
- SDTM datasets
SDTM datasets
SDTM datasets- ADaM datasets
ADaM datasets
ADaM datasets- Tables, Listings, and Figures (TLFs)
Tables, Listings, and Figures (TLFs)
Tables, Listings, and Figures (TLFs)- Ensure all deliverables are compliant with CDISC standards and regulatory requirements
Ensure all deliverables are compliant with CDISC standards and regulatory requirements
CDISC standards- Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission‑ready datasets, and reviewer’s guides
Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission‑ready datasets, and reviewer’s guides
regulatory submissions- Serve as a Principal‑level programmer, providing technical leadership and guidance to other programmers as needed
Serve as a Principal‑level programmer, providing technical leadership and guidance to other programmers as needed
Principal‑level programmer- Contribute to and help maintain programming standards, macros, and validation processes
Contribute to and help maintain programming standards, macros, and validation processes
programming standards, macros, and validation processes- Review and approve programming deliverables to ensure accuracy, consistency, and quality
Review and approve programming deliverables to ensure accuracy, consistency, and quality
- Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
- Proactively identify risks and propose efficient, compliant solutions within timelines
Proactively identify risks and propose efficient, compliant solutions within timelines
Required Qualifications
Required Qualifications- Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
- Extensive experience as a statistical programmer, with demonstrated Principal‑level responsibilities
Extensive experience as a statistical programmer, with demonstrated Principal‑level responsibilities
statistical programmerPrincipal‑level responsibilities- Strong hands‑on experience with:SDTM and ADaM dataset developmentTLF programmingRegulatory submission deliverables
Strong hands‑on experience with:
- SDTM and ADaM dataset development
SDTM and ADaM dataset development
SDTM and ADaM- TLF programming
TLF programming
TLF programming- Regulatory submission deliverables
Regulatory submission deliverables
Regulatory submission deliverables- Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
and Advanced SAS with good hands on SAS Macros- In‑depth knowledge of CDISC standards, regulatory guidelines, and submission requirements
In‑depth knowledge of CDISC standards, regulatory guidelines, and submission requirements
CDISC standards- Proven ability to manage complex studies independently from start to finish
Proven ability to manage complex studies independently from start to finish
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
https://jobs.iqvia.comIQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
https://jobs.iqvia.com/eoeIQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
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