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Job Openings Principal Process Engineer - API External Manufacturing Small Molecule About the job Principal Process Engineer - API External Manufacturing Small Molecule Job Title: Principal Process Engineer - API External Manufacturing Small Molecule Job Location: Indianapolis, Indiana, United States of America Job Location Type: Remote Job Contract Type: Full-time Job Seniority Level: At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Position Brand Description: The position of Principle Process Engineer - API EM Small Molecule reports to the API EM Engineering Director and provides technical leadership and expertise in conjunction with API EM contract manufacturer personnel in the reliable supply and commercialization of medicines with safety first and quality always by: Developing and sustaining process knowledge in order to ensure the execution of the appropriate product, process, and operational control strategy at a number of Contract Manufacturers (CMs)Assessment of the suitability of proposed equipment sets to ensure success of process validationsDirect and Indirect interaction with CM personnel to ensure reliable supply via the CM execution of the operational control strategyFUME assessment to ensure an understanding of risk presented to the operational control strategyParticipation with internal or CM resources in the equipment specification, procurement, and IQ/OQ/PQParticipation with internal and CM resources to assess the HSE and PSM elements of the CM that impact Lilly productsEngaged with internal and external resources in developing capabilities with new or evolving technologies that may impact delivery of internal or external portfolio assets.Adherence to the expectations of the Lilly Red Book when carrying out interactions with API EM’s CMs.Key Objectives/Deliverables:Coach and Mentor Process Team MembersUtilize past experiences with unit operation control to provide insight and feedback to members of the CM Joint Process Team (JPT).Champion the application of statistical thinking and use of data to monitor process performance and make engineering decisions with CM members of the JPT.Support and peer review root cause analysis around FUME and operational incidents.Peer review documentation of learning points, technical studies, and incident investigations.Scale‑Up & Tech TransferLead/support tech transfers and scale‑up from development through PV and commercial supply.Translate process intent into operating strategies, equipment fit/gap, batch documentation, and PV readiness at CMs.Support engineering runs and PV readiness through parameter optimization and performance trending.Develop and Sustain Process KnowledgeIdentify process knowledge gaps that impact equipment and process capability.Develop or support the capture of key process knowledge (examples include material and energy balances, kinetics, chemistry, process modeling, and equipment design basis).Enable the development and maintenance of process knowledge. infrastructure such as key models, report history, lab models, and literature.Utilize optimization resources and tools for process analysis and process improvement studies.Review and track key process engineering metrics.Provide Process & Equipment Support:Identify systemic issues affecting production and reliable supply from CMsLead or participate in root cause analysis and countermeasure development and implementation for major safety, quality, or throughput incident investigations. Perform reviews of incident documentation for technical accuracy.Review and approve documentation and engineering decisions.Process Optimization & Continuous Improvement:Support development and technical analysis for on-going continuous improvement activities.Review and identify cost reduction opportunities, as well as process capacities and bottlenecks. Assist in prioritization of opportunities with respect to overall business objectives.Work with the CMs to ensure the application of statistical thinking and methods to understand process variability and capability.Perform and promote optimization of unit operation cycle time, loading, and yield performance.Engage with late phase development and Engineering Technical Center resources to ensure staying contemporary with key engineering disciplines and developing portfolio platforms (e.g. continuous manufacturing operations).Equipment Capability and Asset Management:Create an appropriate methodology to ensure visibility of the ongoing state of qualification of key FUME systems at the CMs.Review equipment and process system user requirements and qualification plans to ensure that the equipment and systems are appropriate for the intended purpose.Act as customer representative for review of Contact Manufacturer (CM) requests for capital projects targeted at both short- and long-term needs.Oversight of HSE and PSM:Serve as the liaison for API EM and Global HSE on health, safety, and environmental (HSE) and process safety management (PSM) oversight at the relevant contract manufacturing sites.Leverage internal Lilly experts in HSE and PSM to ensure appropriate risk reduction at CMs.Participate in Lilly HSE and PSM audits of contract manufacturing sites as applicable.Maintain key HSE and PSM metrics for review within API EM. Adherence to Business, Quality, and Financial Systems:Understand and follow all applicable Lilly policies and procedures with respect to interactions and oversight of API contract manufacturing sites. Basic Requirements:Bachelor of Science degree in Chemical Engineering, or another engineering discipline with extensive chemical manufacturing experience.3+ years of work experience in a manufacturing/process engineering related role related to small molecules.Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.Additional Preferences:Experience in typical unit operations for Small Molecule API ManufacturingDeep technical knowledge of API / Drug Substance manufacturing equipment and unit operations.Demonstrated ability to apply fundamental chemical engineering principles to process understanding, problem solving, and process improvement.Demonstrated ability to function in a team environment as a technical leader and as a member of teams.Demonstrated ability to manage and prioritize competing priorities and to appropriately communicate verbally and in writing to various audiences.Develop and implement innovative approaches to problemsProcess Hazard Analysis experienceSuccessful application of root cause analysis and systematic problem solvingStrong Computer skills in a variety of software packages ( e.g Batch Plus, JMP, Visio, Aspen, Dynochem, OSI PI, MS Office Suite).Visualize an operation/process and reflect it in a model.Other Information: This role is located onsite in Indianapolis, IN with the ability to work from home up to 4 days per month. Relocation assistance will be provided if applicable.This role is not approved for 100% remote workTravel may routinely be required to support process start-ups, troubleshooting, and commercial manufacturing. This travel is typically in the range of 15% to 25% annually, depending on the needs of the process(s).Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is$66,000 - $171,600Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.#WeAreLillyThis job is curated by Lifelancer. Lifelancer is a talent-hiring platform in Life Sciences, Pharma and IT. The platform connects talent with opportunities in pharma, biotech, health sciences, healthtech and IT domains. Please apply via Lifelancer platform to get connected to the application page and to find similar roles. Apply for Position Or refer someone Share Facebook Line LinkedIn X (Formerly Twitter) Whatsapp EmailRemotePrincipal$66K–171.6K
posted 10 days ago
Skip to main content<div class="container-fluid"><div class="alert alert-error"><strong>WARNING:</strong>Your JavaScript is disabled. This site does not work without JavaScript. Please enable JavaScript to use all features.</div></div>#apply-button { background-color: #747480; border: #747480; } #omb { position: absolute; top: 60px; right: 0; padding: 5px; background-color: white; };English简体中文中文EnglishFrançaisDeutschItaliano日本語한국어PolskiPortuguêsEspañolEnglish简体中文 - Chinese (Simplified)中文 - Chinese (Traditional)English - EnglishFrançais - FrenchDeutsch - GermanItaliano - Italian日本語 - Japanese한국어 - KoreanPolski - PolishPortuguês - PortugueseEspañol - SpanishShow MoreTax Consultant - Global Compliance & Reporting - Diegem - Industries 11730549BEL-Diegemapply_________At EY, our Tax professionals are dedicated to helping clients navigate complex tax regulations and optimize their financial strategies. We provide expert guidance to businesses and individuals, ensuring they remain compliant and achieve their financial objectives in a constantly evolving tax landscape.You will not be limited to a specific sector, allowing you to work with clients across various industries, including transport, logistics, manufacturing, oil & gas, pharma, retail, service providers, etc. This is applied to all of our service lines: Assurance, Consulting, EY Parthenon, Tax & Legal and Accounting, Compliance & ReportingShape the future with confidence. The Opportunity: Your Next Adventure Awaits? Within Corporate Tax, we are looking for a consultant to join our Global Compliance & Reporting team in the Diegem office.Our Global Compliance &Reporting team assists both international and Belgian companies with e.g. direct tax compliance and reporting obligations, tax controversy, tax accounting reporting, tax risk management, tax on site assistance and tax function assessments. Closely collaborating with financial and accounting experts, Global Compliance & Reporting dives into the financial data of our clients to translate it into tax solutions. By closely teaming with our other tax & law specialists, our aim is to be the trusted business advisor for our clients.In this role, you will help guide our clients through the complexities of tax reporting and contribute to shaping the future of corporate tax services. Your Key ResponsibilitiesAs a Consultant in the Global Compliance & Reporting department, you will support the team in their day-to-day activities and help them with preparatory work. Your role will consist of supporting with the following tasks that are part of the package of our team members:Familiarize yourself with the financial reporting processes of our clients, focusing on the financial data impacting their tax position.Ensure our clients comply with all relevant Belgian tax compliance obligations and assist them with day-to-day Belgian tax compliance services, including assistance during tax audits. The implementation of Pillar II and other international tax legislation into our Belgian compliance processes is part of this compliance package.Identify and implement process improvements in our clients’ tax compliance processes.Pro-actively follow up, communicate and collaborate with the team regarding your assigned client portfolio.Be eager to learn and stay up-to-date with the latest changes within the Belgian tax legislation.Adopt fast changing technologies and digital transformations.Assist with the preparation of client proposals, internal and external presentations and client meetings.You will stay up-to-date regarding market changes and develop a broader knowledge around your client portfolio.Work effectively as a member of a worldwide network of professional advisors, sharing responsibility, providing support, maintaining communication and updating senior team members on progress. Your Profile You have/are:finishing your Bachelor in accountancy, tax and/or finance /Master’s degree in economics or law (a supplementary degree in fiscal matters is a plus).Client and market focused, team player, stress resistant and an excellent communicator.Desire to learn and develop into the role.Fluent in French or Dutch and good knowledge of English. What’s In It For You EY Family – you become part of the EY Family providing you with all the necessary skills, training and opportunities; enabling you to grow to your fullest potential. Attractive remuneration package - We offer an attractive remuneration package; including a company car and charging card, iPhone plus subscription, health insurance, pension plan, meal vouchers, and eco vouchers. Thanks to our flex plan it is possible to choose what you value most. Mobility package - You’ll be able to opt-in for the mobility budget. In return for giving up your (right to a) company car, you’ll receive a monthly budget from EY as compensation. This budget will allow you to use your employer-provided compensation for alternative transportation means or similar benefits, incl. reimbursement of housing costs (on condition you live within 10km of your main place of employment). Flexible working arrangements - We are proud of our flexible working arrangements. We will actively support you in building a successful career and delivering excellent client service without sacrificing your personal priorities. We offer flexible working hours and working from home multiple days per week is possible.Inspiring work environment - At EY we are dedicated to providing you with an inspiring work environment. A work environment that allows you to further develop your skills and enables you to fulfill your true potential.Learning & personal growth - You will benefit from an onboarding program, receive extensive training and will be coached by a counselor. We offer a clear career path tailored to your unique skills with necessary guidance. Fun - By joining our EY- teams, you can participate in team activities, and companywide events and enjoy a drink during our monthly after-work drink. Sustainability - We have a fleet of hybrid and electric cars. Our flex plan makes it possible for you to choose the most sustainable option for you. You can also opt for a train subscription or lease a bike. Diversity & Inclusion - At EY we are passionate about the inclusion and support of individuals of all groups; we do not discriminate on the basis of race, religion, gender, sexual orientation, or disability status. Location - All of our offices are easily accessible by public transport and/or by car and have parking space. They all have parking spaces and charging stations are provided. Share:Service Line/Business AreaTaxCountry/RegionBelgiumShare:<transition name="modal"><div class="modal-mask"><div class="modal-wrapper"><div class="modal-container"><div class="modal-body jobs-modal"><section class="left"><h4>Important Notice</h4><p>You are being redirected to complete your application.</p></section><section class="action-buttons"><button class="btn btn-primary btn-cancel" id="cancel-button" v-on:click="$emit("close")">Cancel</button><a class="btn btn-primary btn-apply" id="apply-button" target="_blank" v-on:click="$emit("close")">Continue</a></section></div></div></div></div></transition>Powered byCookie PreferencesEntry Level
posted 21 days ago
Skip to main content<div class="container-fluid"><div class="alert alert-error"><strong>WARNING:</strong>Your JavaScript is disabled. This site does not work without JavaScript. Please enable JavaScript to use all features.</div></div>#apply-button { background-color: #747480; border: #747480; } #omb { position: absolute; top: 60px; right: 0; padding: 5px; background-color: white; };English简体中文中文EnglishFrançaisDeutschItaliano日本語한국어PolskiPortuguêsEspañolEnglish简体中文 - Chinese (Simplified)中文 - Chinese (Traditional)English - EnglishFrançais - FrenchDeutsch - GermanItaliano - Italian日本語 - Japanese한국어 - KoreanPolski - PolishPortuguês - PortugueseEspañol - SpanishShow MoreTax Consultant - Global Compliance & Reporting - Hasselt- Industries 11730170BEL-Antwerpen / Berchemapply_________At EY, our Tax professionals are dedicated to helping clients navigate complex tax regulations and optimize their financial strategies. We provide expert guidance to businesses and individuals, ensuring they remain compliant and achieve their financial objectives in a constantly evolving tax landscape.You will not be limited to a specific sector, allowing you to work with clients across various industries, including transport, logistics, manufacturing, oil & gas, pharma, retail, service providers, etc. This is applied to all of our service lines: Assurance, Consulting, EY Parthenon, Tax & Legal and Accounting, Compliance & ReportingShape the future with confidence. The Opportunity: Your Next Adventure Awaits? Within Corporate Tax, we are looking for a consultant to join our Global Compliance & Reporting team in the Antwerp/Hasselt office.Our Global Compliance &Reporting team assists both international and Belgian companies with e.g. direct tax compliance and reporting obligations, tax controversy, tax accounting reporting, tax risk management, tax on site assistance and tax function assessments. Closely collaborating with financial and accounting experts, Global Compliance & Reporting dives into the financial data of our clients to translate it into tax solutions. By closely teaming with our other tax & law specialists, our aim is to be the trusted business advisor for our clients.In this role, you will help guide our clients through the complexities of tax reporting and contribute to shaping the future of corporate tax services. Your Key ResponsibilitiesAs a Consultant in the Global Compliance & Reporting department, you will support the team in their day-to-day activities and help them with preparatory work. Your role will consist of supporting with the following tasks that are part of the package of our team members:Familiarize yourself with the financial reporting processes of our clients, focusing on the financial data impacting their tax position.Ensure our clients comply with all relevant Belgian tax compliance obligations and assist them with day-to-day Belgian tax compliance services, including assistance during tax audits. The implementation of Pillar II and other international tax legislation into our Belgian compliance processes is part of this compliance package.Identify and implement process improvements in our clients’ tax compliance processes.Pro-actively follow up, communicate and collaborate with the team regarding your assigned client portfolio.Be eager to learn and stay up-to-date with the latest changes within the Belgian tax legislation.Adopt fast changing technologies and digital transformations.Assist with the preparation of client proposals, internal and external presentations and client meetings.You will stay up-to-date regarding market changes and develop a broader knowledge around your client portfolio.Work effectively as a member of a worldwide network of professional advisors, sharing responsibility, providing support, maintaining communication and updating senior team members on progress. Your Profile You have/are:finishing your Bachelor in accountancy, tax and/or finance /Master’s degree in economics or law (a supplementary degree in fiscal matters is a plus).Client and market focused, team player, stress resistant and an excellent communicator.Desire to learn and develop into the role.Fluent in French or Dutch and good knowledge of English. What’s In It For You EY Family – you become part of the EY Family providing you with all the necessary skills, training and opportunities; enabling you to grow to your fullest potential. Attractive remuneration package - We offer an attractive remuneration package; including a company car and charging card, iPhone plus subscription, health insurance, pension plan, meal vouchers, and eco vouchers. Thanks to our flex plan it is possible to choose what you value most. Mobility package - You’ll be able to opt-in for the mobility budget. In return for giving up your (right to a) company car, you’ll receive a monthly budget from EY as compensation. This budget will allow you to use your employer-provided compensation for alternative transportation means or similar benefits, incl. reimbursement of housing costs (on condition you live within 10km of your main place of employment). Flexible working arrangements - We are proud of our flexible working arrangements. We will actively support you in building a successful career and delivering excellent client service without sacrificing your personal priorities. We offer flexible working hours and working from home multiple days per week is possible.Inspiring work environment - At EY we are dedicated to providing you with an inspiring work environment. A work environment that allows you to further develop your skills and enables you to fulfill your true potential.Learning & personal growth - You will benefit from an onboarding program, receive extensive training and will be coached by a counselor. We offer a clear career path tailored to your unique skills with necessary guidance. Fun - By joining our EY- teams, you can participate in team activities, and companywide events and enjoy a drink during our monthly after-work drink. Sustainability - We have a fleet of hybrid and electric cars. Our flex plan makes it possible for you to choose the most sustainable option for you. You can also opt for a train subscription or lease a bike. Diversity & Inclusion - At EY we are passionate about the inclusion and support of individuals of all groups; we do not discriminate on the basis of race, religion, gender, sexual orientation, or disability status. Location - All of our offices are easily accessible by public transport and/or by car and have parking space. They all have parking spaces and charging stations are provided. Share:Service Line/Business AreaTaxCountry/RegionBelgiumShare:<transition name="modal"><div class="modal-mask"><div class="modal-wrapper"><div class="modal-container"><div class="modal-body jobs-modal"><section class="left"><h4>Important Notice</h4><p>You are being redirected to complete your application.</p></section><section class="action-buttons"><button class="btn btn-primary btn-cancel" id="cancel-button" v-on:click="$emit("close")">Cancel</button><a class="btn btn-primary btn-apply" id="apply-button" target="_blank" v-on:click="$emit("close")">Continue</a></section></div></div></div></div></transition>Powered byCookie PreferencesEntry Level
posted 21 days ago
CA - Canada; US - Culver City, United StatesPrincipal$169.6K–250K
verified Jun 21, 2026posted 3 months ago
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verified Aug 5, 2026posted 3 months ago
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